Hi @Drover , would way out of balance (on that wheel only) cause uneven wear on van as it does on cars and tugs??
It can show as a small flat spot on tread which can be an out of round tyre and/or balance, it can also be from a wheel locking up and making a flat spot which in turn will have the wheel out of balance, it also throws other problems as well, serious wobble could cause bearing fail/wear even studs could be stressed but in those cases you would certainly feel the shuddering........ something to check when the cupboards start shedding screws while driving on good roads.
If you look at your rims, on car or trailer and they have a heap of weights stuck inside (alloy) or hanging off the edge (steel) then take them in to a proper tyre shop and get them properly balanced, lots of lead show the person balancing that wheel didn't know what he was doing and he was chasing the bubble, its an art to balance properly and at times requires moving the tyre around the rim, the less weight added the better the trim. On new tyres they should have red and/or yellow dots they show certain things which I forget which is which now but should be inline or very close to the valve stem and aid balance, so less weights needed............... if they want to fit bang on weights on alloy rims go somewhere else, stick on only no lead banged on anywhere.